Table 1.
Study population characteristics and comparison between survivor and fatality groups.
Continuous variables are presented as mean±SD or median (25th–75th percentile). The proportions in this table reflect the number of patients with each finding divided by the total number of patients for whom data were available.
Fig 1.
Flow chart for the selection of the participating patients, according to the STROBE guidelines.
HSJ—Hospital São João, Porto, Portugal; CDC—Chest Disease Centre (ambulatory care), Vila Nova de Gaia, Portugal.
Table 2.
Multivariable logistic regression analysis for deriving tuberculosis risk score for death.
Fig 2.
A—ROC curve for the logistic regression model (clinical prediction rule equation, S1 Fig) and clinical scoring system (0 to 8 points) | B—Kaplan-Meier estimates of survival in low-risk (clinical score 0–2), moderate-risk (clinical score 3–5) and high-risk (clinical score 6–8) tuberculosis patients. The mortality in each group at different time-points is shown below | C—TB risk assessment tool (TReAT), using baseline clinical features for stratifying patients with pulmonary tuberculosis into severity groups according to the probability of death at 6 months.
Table 3.
Test characteristics with different prediction scores for mortality in the derivation cohort of patients with pulmonary tuberculosis.
Table 4.
Comparison of risk groups mortality in the derivation and validation cohortsa.