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Fig 1.

Flow chart of participants in the study.

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Table 1.

Demographics and clinical characteristics of the TTBI and no TTBI groups at baseline.

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Table 2.

Comparison of the changes (between the baseline and at 12 months) of quality of life, motor and psychological scale scores for both groups.

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Fig 2.

Evaluation of the change in PDQ-39 score between the baseline and at 12 months in the two groups of PD patients.

The spider chart shows the difference in each PDQ-39 dimension between the baseline and at 12 months. The dotted line indicates an absence of change in the PDQ-39 score over the 12-month period. Quality of life improved when the point plotted is below the dotted line and worsened when it is above the dotted line.

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Table 3.

Economic analysis: patient characteristics and costs.

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Fig 3.

95% credible region of the ICER using the confidence ellipse method.

These figures show the cost-effectiveness plane for therapeutic education in PD compared to conventional care based on 1000 bootstrap estimates of the difference in cost and effectiveness. Incremental effectiveness and incremental cost are plotted on the horizontal and vertical axes, respectively. Each dot represents the ICER for one simulation. Lozenges represent the observed ICER. Ellipses represent a 95% confidence region around the ICER for the therapeutic education strategy compared to conventional care. Most of the dots are found in the left areas, showing that therapeutic education is cost-effective (more effective and more costly) or cost saving (more effective and less costly).

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