Table 1.
Clinical and demographic data of the study cohort.
Table 2.
Morphological data.
Fig 1.
Representative T1-weighted MP-RAGE image (left) with color overlay of segmented deep gray matter structures, R2* relaxation rate constant map (center) and quantitative susceptibility map (right) of a 62-years patient with PD (MDS-UPDRS 46; Hoehn & Yahr 2).
High R2* rates and paramagnetic susceptibilities are found in the basal ganglia. Note the improved gray-white matter contrast on the QSM map compared to the R2* map.
Fig 2.
Regional mean susceptibilities and R2* (±standard deviation).
Asterisks denote significant differences between controls and patients with Parkinson’s disease (*p<0.05; **p<0.01; ***p< = 0.001).
Table 3.
Regional magnetic susceptibility and R2* values.
Table 4.
Univariate correlations of R2* and magnetic susceptibility with clinical parameters for patients with PD.
Table 5.
Univariate correlations of R2* and magnetic susceptibility for patients with shorter and longer disease duration dichotomized by median disease duration (3.4 years).