Fig 1.
Design and material breakdown (left). Assembled valve cross-section showing the control and flow channels (right). Applied fluidic pressure to the control channel actuates the valve by deforming the flexible membrane to obstruct the flow channel.
Table 1.
Requisite Closure Pressures.
Fig 2.
Experimental setup used to characterize printed fluidic valves.
Pneumatic regulators were used for control channel actuation and to pressurize the liquid chamber along with solenoid valves. Pressure sensors connected to an Arduino UNO microcontroller were used to record both control channel and liquid chamber pressures.
Fig 3.
Fluid flow under various conditions.
Measurements of fluid flow through the 3D printed multimaterial valve with varying applied pressure to the control channel are plotted. Dimensions and materials were varied according to Table 1, with a standard membrane thickness of 300 μm, control channel width of 800 μm, control channel height of 800 μm, and a semi-circular flow channel radius of 400 μm. Proportional control of the flow rate is demonstrated and the design parameters are explored through varying membrane thickness (top), control channel width (middle), and membrane material (bottom). Connecting lines are shown only for visualization and the charted points and error bars represent the measured data. For membrane thickness and control channel width, two prints of each design file were tested and each is plotted using the average of two trials per print. The bracketed number in the legend indicates a different print of the same design file and both are plotted for clarity with the same color. Membrane material type tests used a single print. Error bars show repeatability between trials at the same pressure for different prints of the same valve specifications (± 4.4 psi, calculated with 95% confidence interval). Listed stiffness values for the membrane material are sourced from Stratasys, Ltd. Material data sheets [25]. Please see the Supporting Information for all of the data from the trials.
Fig 4.
3D printed microfluidic valves.
A) A 3D printed single material multichannel valve system (top left) and a 3D printed multimaterial multichannel valve system (bottom left). The single material valve contains two control channels with square chambers both above and below the flow channels and the multimaterial valve uses the same design methodology previous described in the paper. For the multimaterial multichannel valve, all channel valves are actuated at the same time by the control line. The global deformation of the single material valve system is significantly larger than the multimaterial valve during actuation, as seen in S1 Video B) A 3D printed multimaterial valve with chemiluminescent liquid in the control and flow channels for visualization (right).
Fig 5.
A product-scale wearable millifluidic system 3D printed with an experimental liquid support technique.
The digitally designed and fabrication system was printed with colleagues [32] and future work will look to further characterize this experimental printing method. For the images, a chemiluminescent liquid was pumped through the flow channels for visualization.