Table 1.
Study Design Timeline (Exposure Day).
Table 2.
Summary mean (SD) of subject anthropometric and baseline lung function data.
Table 3.
Mean (SD) decrements in lung function variables (delta % fall) expressed as ((Pre-Post Ozone)/Pre Ozone)–(Pre-Post Air)/Pre Air)) X 100.
Table 4.
Responder defined by 20% fall in FEV1 at ≤ 10mg/ml. PD20 = dose at which FEV1 falls by ≥ 20%.
Table 5.
Breathing patterns (mean (SD)) measured by respiratory inductance plethysmography.
N = 18 for obese, one subject’s data was not recorded.
Table 6.
Sputum PMNs (concentration and %of recovered cells) and Sputum IL-6 concentration (pg/ml).
Table 7.
Summary (mean and SD) of baseline plasma adipose hormones and chemokines (average of two pre-exposure for each subject).
Fig 1.
Mean (SE) plasma IL-6 concentrations for pre- vs. post-air and pre- vs. post-ozone exposure.
Pre-exposure levels of IL-6 were less in normal weight than obese (Table 7). Both groups show significant increase in IL-6 4-hours post ozone exposure (P < 0.005). *P < 0.006 for Obese vs. Normal 4-hours post-ozone exposure.