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Fig 1.

Study design.

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Table 1.

Baseline characteristics of the study population.

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Table 2.

Baseline characteristics after randomization.

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Table 3.

Unadjusted comparisons of individual and composite symptom intensity scores before, during, and after the neuromuscular strain maneuvera.

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Table 4.

Mean difference and 95% confidence intervals (CI) between groups for changes in symptom intensity scores during and 24 hours after the maneuver, adjusted for baseline values.

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Table 5.

Group comparisons of increases of at least 2 points in symptom intensity during and 24 hours after the maneuver.

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Fig 2.

Proportion of CFS participants reporting a ≥ 2 point increase in symptom intensity for any 1, 2, or 3 symptoms (a) during the straight leg raise or sham neuromuscular strain or (b) 24 hours post-maneuver.

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