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Fig 1.

Consort flowchart.

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Fig 2.

Glucose.

Fasting glucose values at baseline (T1) and after four days of dexamethasone treatment (T2). N = 42.

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Fig 2 Expand

Table 1.

Laboratory measurements.

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Table 1 Expand

Fig 3.

Insulin.

Insulin values at baseline and after four days of dexamethasone treatment. N = 40.

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Fig 4.

HOMA-IR.

HOMA-IR values at baseline and after four days of dexamethasone treatment. N = 39.

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Fig 4 Expand

Fig 5.

Lipids and glucose.

Dexamethasone-induced change in HDL, LDL, total cholesterol, triglycerides, and glucose (mmol/L) from T1 to T2. * = P<0.05 and ** = P<0.01 (Student’s paired t-test). The horizontal lines indicate the median change.

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Fig 6.

Blood pressure.

Dexamethasone-induced changes in diastolic and systolic blood pressure (BP) SDS values after four days of dexamethasone treatment. N = 43. * = P<0.05 and ** = P<0.01 (Wilcoxon signed-rank test). The horizontal lines indicate the median change.

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Table 2.

Components of the metabolic syndrome.

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Table 2 Expand

Fig 7.

Dexamethasone levels and glucose.

Glucose levels measured at T2 plotted against dexamethasone trough serum levels for each patient (N = 24). The two values were significantly correlated (Spearman’s coefficient (r): 0.63, P<0.01).

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Fig 7 Expand