Fig 1.
Example of bSSFP cine images in diastole used for wall thickness measurements.
Measurement locations are shown at the inferior RV wall (RVI thickness, white arrowhead), interventricular septum (IVS thickness, black arrowhead), and inferior LV wall (LVI thickness, open arrowhead) for a subject with pulmonary hypertension (A) and Anderson-Fabry disease (B). Light grey arrows show areas of RV epicardial fat. Note the absence of readily visible epicardial fat along the inferior RV wall.
Fig 2.
Example SASHA T1-mapping case.
A) Sample SASHA T1-mapping images in a subject with Anderson-Fabry disease, showing septal (solid white), inferior right ventricle (dashed black), and inferior left ventricle (dashed white) regions of interest (ROI). B) Sample T1 map is shown. C) Mean signal intensity from the right ventricle ROI from this subject are plotted with the corresponding saturation recovery time (TS), along with a best-fit saturation recovery curve defined by the displayed equation. Black arrows indicate the saturation recovery images shown in A). D) A zoomed in portion showing the inferior RV wall, along with the corresponding ROI. Note the absence of visible pericardial fat in this location. The dark signal in the left ventricle lateral wall is a site of positive late gadolinium enhancement.
Table 1.
Subject characteristics.
Table 2.
CMR variables.
Fig 3.
Myocardial T1 values by ventricle and condition.
Data is presented as boxes representing the 25th, 50th, and 75th percentiles, and fences representing 1.5× interquartile range.