Fig 1.
H03_01TP and H03_02TP study flow charts.
Table 1.
Absolute Neutrophil Counts Grading.
Fig 2.
CRC305A and CRC305C study flow charts.
Fig 3.
Ghent trial study flow chart.
Table 2.
First PubMed Search Results.
Table 3.
PubMed Search Strings.
Fig 4.
Literature search flow-chart.
Table 4.
Vaccines Associated With Neutropenia Cases in Articles Selected in the Literature Search.
Fig 5.
Absolute neutrophil count at different time points after vaccination with three doses of either 1790GAHB or placebo at 0, 1, and 2 months.
(A) H03_01TP study. (B) H03_02TP study. Red dots indicate subjects who had an absolute neutrophil count less than laboratory normal range on at least one time point after vaccination. Baseline data are collected during the screening of volunteers. Bars indicate median and interquartile range. At each time point, dots relating to ANC in vaccinees are on the left hand side and dots relating to ANC in placebo recipients are on the right hand side.
Table 5.
Grade 3 Cases of Neutropenia Occurred in two Trials After Administration of the First Dose of the Shigella GMMA Vaccine.
Fig 6.
Absolute neutrophil count at different time points after vaccination on day 0.
(A & B) adjuvanted seasonal TIV. (C) seasonal TIV. (D) attenuated live yellow fever vaccine. (A, C & D) conducted as inpatients. (B) conducted as outpatients. Red dots indicate subjects who had an absolute neutrophil count less than laboratory normal range on at least one time point after vaccination. Bars indicate median and interquartile range.