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Fig 1.

Engineering drawing of the bi-leaflet valve (GV valve) with the replica of the GD valve prototype.

All dimensions in mm.

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Fig 1 Expand

Fig 2.

Schematic of experimental set up configured for particle image velocimetry. Arrows denote flow direction.

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Fig 2 Expand

Fig 3.

Samples of mitral waveforms observed.

(a) A mitral flow waveform sample observed in the Epic Valve experiment. (b) A mitral flow waveform sample observed in the GD Valve experiment. (c) A LV pressure waveform sample observed in the Epic and GD valve experiment.

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Fig 3 Expand

Table 1.

Summary of physiological parameters during PIV.

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Table 1 Expand

Fig 4.

Velocity flow fields.

(a) Velocity field [ms-1] of the Epic valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV. (b) Velocity field [ms-1] of the GD bileaflet valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV.

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Fig 5.

MKE [Jm-3] contour plots.

(a) MKE [Jm-3] contour plot of the Epic valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV. (b) MKE [Jm-3] contour plot of the GD valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV. (c) A comparison of the average MKE [Jm-3] values in the left ventricle between EV and GD valves over 7 time points in 1 cardiac cycle. Poly—refers to fitted values by polyline.

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Fig 5 Expand

Fig 6.

Vorticity and Circulation plots.

(a) Net vorticity [s-1] contour plot of the Epic valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV. (b) Net vorticity [s-1] contour plot of the bileaflet GD valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV. (c) Total circulation in the left ventricle for both valves over 7 time steps in 1 cardiac cycle. Poly—refers to fitted values by polyline. (d) Normalized vorticity in the left ventricle for both valves over 7 time steps in 1 cardiac cycle. Poly—refers to fitted values by polyline. (e) Clockwise vorticity in the left ventricle for both valves over 7 time steps in 1 cardiac cycle. Poly—refers to fitted values by polyline. (f) Clockwise circulation in the left ventricle for both valves over 7 time steps in 1 cardiac cycle. Poly—refers to fitted values by polyline.

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Fig 6 Expand

Fig 7.

RSS [Pa] contour plots.

(a) RSS [Pa] contour plot of the Epic valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV. (b) RSS [Pa] contour plot of the bileaflet GD valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV.

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Fig 7 Expand

Fig 8.

TKE [m2s-2] contour plots.

(a) TKE [m2s-2] contour plot of the Epic valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV. (b) TKE [m2s-2] contour plot of the bileaflet GD valve in the left ventricle over 7 time steps in 1 cardiac cycle. Shaded area denotes area of interest measured by PIV.

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Fig 8 Expand

Fig 9.

Left ventricular turbulence intensity for both valves over 7 time steps in 1 cardiac cycle.

Poly—refers to fitted values by polyline.

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Fig 9 Expand