Table 1.
Cytokines concentrations in L-PRP.
Table 2.
Characteristics of patients included in the two treatment groups.
Table 3.
Baseline plasma and synovial fluid cytokines concentrations.
Fig 1.
Plasma and synovial fluid concentration of IL-1b and IL-6 in patients treated with L-PRP or HA.
Data are expressed as medians and interquartile ranges; comparisons among time points, as determined by Friedman-ANOVA test, and between L-PRP and HA treatments, as determined by the Mann-Whitney U test, are not significant. w = week, m = month
Fig 2.
Plasma and synovial fluid concentration of IL-8 and IL-17 in patients treated with L-PRP or HA.
Data are expressed as medians and interquartile ranges; comparisons among time points, as determined by Friedman-ANOVA test, and between L-PRP and HA treatments, as determined by the Mann-Whitney U test, are not significant, excluded the comparison between IL-8 concentration in the synovial fluids at w2, p<0.05. w = week, m = month
Fig 3.
Plasma and synovial fluid concentration of IL-4, IL-10 and IL-13 in patients treated with L-PRP or HA.
Data are expressed as medians and interquartile ranges; comparisons among time points, as determined by Friedman-ANOVA test, and between L-PRP and HA treatments, as determined by the Mann-Whitney U test, are not significant. w = week, m = month
Table 4.
Growth Factors levels in L-PRP.
Fig 4.
Synovial fluid concentration of FGF-b, HGF and PDGF-AB/BB in patients treated with L-PRP or HA.
Data are expressed as medians and interquartile ranges; comparisons among time points, as determined by Friedman-ANOVA test, and between L-PRP and HA treatments, as determined by the Mann-Whitney U test, are not significant. w = week