Fig 1.
Antimicrobial susceptibility of E. coli and Salmonella enterica isolates of diverse serovars in aerobic and anaerobic conditions after a 24-hour adaptation to the conditions prior to the testing.
Box-plots of the differences in susceptibility of the isolates between aerobic and anaerobic conditions (the p-value of the Wilcoxon signed rank test for each difference is included). Legend: I—Ampicillin. II—Ceftriaxone. III—Gentamicin. IV–Kanamycin. V–Enrofloxacin. VI–Erythromycin. VII–Azithromycin. VIII–Sulfamethoxazole/Trimethoprim. IX–Tetracycline. On the scatter plots, for each isolate, the solid black circle is the MIC in aerobic test and the hollow blue circle is the MIC in anaerobic test. The isolates are sorted in the order of increasing MIC values in aerobic conditions. For each bacterial species, the black lines denote the distribution of the MIC values across the isolates in aerobic conditions: solid line– 1% quartile, long dash–median, and short dash– 99% quartile. The magenda lines denote the distribution of the MIC values across the isolates of that bacterial species in anaerobic conditions: solid line– 1% quartile, long dash–median, and short dash– 99% quartile.
Table 1.
Descriptive statistics of the MIC distributions, and descriptive statistics and statistical significance of the differences between the MIC values in anaerobic and aerobic conditions for antimicrobials tested (E-Test® on Mueller-Hinton agar) for E. coli and Salmonella enterica of diverse serovars.
Table 2.
Correlations between the relative magnitude of the MIC values of individual isolates of E. coli and Salmonella enterica of diverse serovars in aerobic and anaerobic conditions across the isolates tested (E-Test® on Mueller-Hinton agar).
Fig 2.
Dynamics of changes in antimicrobial susceptibility of individual E. coli (black symbols and lines) and Salmonella enterica (green symbols and lines) isolates of diverse serovars depending on the time of exposure to anaerobic conditions prior to testing the susceptibility in these conditions.
Each isolate is represented by the same symbol in the scatter plot of the susceptibility in aerobic conditions, and the scatter and line plot of the susceptibility in anaerobic conditions. Legend: I–Ampicillin. II–Gentamicin. III–Kanamycin. IV–Enrofloxacin. V–Azithromycin.