Fig 1.
Libyan map showing the collection points Libyan Propolis samples P1 (Alagoria), P2 (Gaminis), P3 (Byda), P4 (Quba), P5,P6, P7 (Kufra), P8(Ghadames), P9 (Tripoli), P10 (Khasr Khiar), P11, P12 (Khumas).
Fig 2.
PCA with HCA based on the 300 most intense features obtained in negative ion mode for the 12 propolis samples R2X 0.689, Q2 0.48.
Table 1.
The top 10 VIPs, composed of negative ion masses measured to within 2 ppm of that of the proposed elemental compositions responsible locating the groups shown in Fig 2.
Fig 3.
OPLS plot of observed against predicted activity against P. falciparum based on five compounds (A-E).
Table 2.
Activity of samples P1-P12 against P.falciparum (n = 3).
Table 3.
Most important variables determining the activity of P2 in anti-protozoal and anti-microbial tests and important variables determining cellular toxicity based on sample P8 which was the most cytotoxic sample.