Fig 1.
Flow diagram of the study.
Table 1.
Patient characteristics of infants with no NEC and definite NEC.
Data are expressed as median (range) or as numbers unless specified otherwise. Abbreviations: NEC—necrotizing enterocolitis; NIRS—near-infrared spectroscopy; PDA—patent ductus arteriosus; PNA—postnatal age; RBC—red blood cell. Circulatory failure was defined as hemodynamic instability and scored by the need for volume expansion or the use of inotropes or both, from one hour before NEC onset until the first forty-eight hours after NEC onset, or until surgery, whichever came first. Statistical differences between the two groups are marked by * (< .05).
Table 2.
RSO2 and FTOE values in the first forty-eight hours after onset of NEC symptoms in preterm infants with no NEC and definite NEC.
Data are expressed as median values with the number of infants studied between brackets. Statistical differences between the two groups are marked by * (< .05).
Table 3.
RSO2 and FTOE values in the first eight hours after onset of NEC symptoms in preterm infants with no NEC and definite NEC.
Only infants with measurements at all 3 locations are included in the analyses. Data are expressed as median values with the number of infants studied between brackets. There were no statistical differences between the two groups.
Table 4.
Patient characteristics of infants with uncomplicated and complicated NEC.
Data are expressed as median (range) or as numbers unless otherwise specified. Abbreviations: NEC—necrotizing enterocolitis; NIRS—near-infrared spectroscopy; PDA—patent ductus arteriosus; PNA—postnatal age; RBC—red blood cell. Circulatory failure was defined as hemodynamic instability and scored by the need for volume expansion or the use of inotropes or both, from 1 hour before NEC onset until the first forty-eight hours after NEC onset or until surgery took place, whichever came first. Differences between the two groups are marked by * (< .05).
Table 5.
RSO2 and FTOE values in the first forty-eight hours after onset of NEC symptoms in preterm infants with uncomplicated and complicated NEC.
Data are expressed as median values with the number of infants studied between brackets. Statistical differences between the two groups are marked by * (< .05).
Table 6.
RSO2 and FTOE values in the first eight hours after onset of NEC symptoms in preterm infants in preterm infants with uncomplicated and complicated NEC.
Data are expressed as median values with the number of infants studied between brackets. Statistical differences between the two groups are marked by * (< .05).
Fig 2.
RcSO2, rlivSO2, and rintSO2 values in infants with no NEC, uncomplicated NEC, and complicated NEC.
Data are shown in box and whisker plots. Dots and stars represent outliers. NoNEC is designated with a plain white boxes; uncomplicated NEC is designated with plain grey boxes, complicated NEC is designated with boxes with grey and white stripes.
Table 7.
Intraindividual variability of preterm infants with no NEC versus preterm infants with definite NEC, and of preterm infants with uncomplicated NEC versus preterm infants with complicated NEC.
Data are expressed as median (range). Abbreviations: NEC, necrotizing enterocolitis; rcSO2, cerebral tissue oxygen saturation; rlivSO2, liver tissue oxygen saturation; rintSO2, infraumbilical tissue oxygen saturation. Intraindividual variability is defined as the daily percentage of time that one-hour mean rSO2 values were 15% or more below or above the infant’s daily mean.