Table 1.
Baseline clinical characteristics of the study population.
Table 2.
HOMA-IR values divided by 10 decile.
Fig 1.
Prevalence of metabolic syndrome according to HOMA-IR.
HOMA-IR: homeostasis model assessment of insulin resistance; Pre-women: premenopausal women; Post-women: postmenopausal women.
Fig 2.
First and second cut-off values of HOMA-IR in men, premenopausal women and postmenopausal women.
The Youden index, calculated as (sensitivity + specificity − 1) was estimated to determine optimal cut-off values. After those subjects with a HOMA-IR lower than the first HOMA-IR cut-off value had been excluded, the data were recalculated to obtain the second cut-off. The first cut-off values in men, premenopausal women, and postmenopausal women were 2.23 (AUC 0.75, sensitivity 70.6%, specificity 66.9%), 2.39 (AUC 0.82, sensitivity 72.3%, specificity 76.4%), and 2.48 (AUC 0.71, sensitivity 51.9%, specificity 80.2%). The second cut-off values in men, premenopausal women, and postmenopausal women were 3.23 (AUC 0.65, sensitivity 48.2%, specificity 76.5%), 3.20 (AUC 0.71, sensitivity 64.8%, specificity 70.8%), and 3.28 (AUC 0.61, sensitivity 45.8%, specificity 71.6%). HOMA-IR: homeostasis model assessment of insulin resistance; Pre-women: premenopausal women; Post-women: postmenopausal women.
Table 3.
Multivariate OR (95% CI) of metabolic syndrome component according to HOMA-IR cut off value.