Table 1.
Year of publication first author and Pubmed ID for the papers used for data extraction, together with individual and combined study sizes and age statistics.
Fig 1.
Root transformed Inhibin B levels.
The red line is the model that best fits the 709 data points, which are indicated by blue squares. The model has r2 = 0.35, indicating that 35% of the variation in inhibin B levels in young males is due to age alone. The green lines represent the upper and lower 95% confidence limits for the predicted mean and the orange lines the upper and lower 95% prediction limits.
Table 2.
Parameter values for the normative model.
The 8 parameter values for the model shown in Fig 2, together with their standard error, T statistics and 95% confidence limits.
Table 3.
300 randomly imputed adult data points were added to our combined data before fitting and comparing normative models. This was repeated for a total of 10 imputations, with model parameters collected for comparison and shown in the numbered columns. For any choice of instance, the parameters are within the 95% confidence intervals for each of the remaining instances.
Fig 2.
The residuals are the variations in root-adjusted observed values from the root-adjusted age-related mean value predicted by the model. The residuals have 97% goodness of fit to an ideal Gaussian curve.
Fig 3.
Inhibin B levels in human males from birth to age 17 years expressed as standard centiles.
Table 4.
Normative Inhibin B levels in pg/mL.
The centiles shown in Fig 3 are here given in tabular form for each year from birth to 17 years.