Table 1.
Patient information for 20 ES cases.
Fig 1.
Immunohistochemical staining of ES for CD99 and Ki-67.
A) CD99 staining, with strong membrane positivity (400×) and B) Ki-67 staining, with strong nuclear positivity (400×).
Fig 2.
Fluorescence in situ hybridization for the assessment of EWSR1 gene rearrangements in ES samples.
Nuclei of tumor cells with EWSR1 rearrangements were detected as red-green split signals as represented by the arrow.
Fig 3.
Overall alteration distribution of 26 genes annotated by the COSMIC database.
A) Mutation frequency of altered genes in 20 ES samples. The blue bars represent alterations in the ES samples, whereas the red bars represent ES samples without alterations. B) Mutation types of the 26 genes. Yellow bars represent missense mutations, and green bars represent nonsense mutations.
Table 2.
Deleterious mutated genes identified in ES samples by IT-PGM.
Table 3.
Mutated genes and corresponding targeted drugs.