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Fig 1.

Potential impact of renal replacement therapy (RRT) on transpulmonary thermodilution (TPTD) with potential impact of catheter positions and blood flow.

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Table 1.

Potential experimental settings.

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Fig 2.

Flow-chart of potential comparisons before, during and after renal replacement therapy (RRT).

Solid lines are used for comparisons aimed at potential real haemodynamic effects of RRT. Dashed lines are given for comparisons aimed at validation of transpulmonary thermodilution (TPTD) technique. MAP: mean arterial pressure. HR: heart rate. PCA: pulse contour analysis. GEDVI: global end-diastolic volume index. EVLWI: extra-vascular lung water index. CI: cardiac index.

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Table 2.

Studies investigating TPTD and PCA in RRT.

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Table 3.

Patients characteristics.

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Table 4.

Haemodynamic parameters over time.

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Fig 3.

Boxplots comparing thermodilution derived cardiac index (CItd) values over time.

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Fig 4.

Boxplots comparing global end-diastolic volume index (GEDVI) values over time.

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Fig 5.

Boxplots comparing central venous pressure (CVP) values over time.

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Fig 6.

ROC-analysis regarding the primary endpoint.

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