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Table 1.

Demographic, immunological and clinical characteristics of 100 selected SSc patients.

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Table 2.

ECG-Holter findings in our cohort of 100 selected SSc patients.

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Table 3.

Clinical characteristics of patients who met the primary end-point (SCD+ICD) compared with patients without major arrhythmic events.

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Fig 1.

Survival curve in patients with and without VEBs>1000/24h.

Kaplan-Meier estimates cumulative survival between patients with or without VEBs>1000/24h. Black line: survival in patients with VEBs>1000/24h. Grey line: survival in patients with VEBs<1000/24. Each tick mark corresponds to a time of patient censoring. None of the patients without VEBs <1000/24h died or required and ICD-implantation during follow-up while 7 patients with VEBs >1000/2h at baseline met the composite end-point SCD/ICD implantation.

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Fig 2.

ROC curve on number of VEBs and major cardiac events.

ROC curve on number of VEBs and major cardiac events (considered as sudden cardiac death or ICD implantation). AUROC = 0.92, p<0.0001. ROC = receiver operating curve. AUROC = area under ROC.

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Table 4.

Clinical characteristics of patients with and without VEBs >1190/24h.

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Table 4 Expand