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Table 1.

Subject characteristics.

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Fig 1.

Ambulation task.

each trial started with subjects in the sitting position in a first chair, from which they stood up, walked 5 m to a second chair, turned 180° before sitting in the second chair, stood up again, walked 5 m back to the starting point, turned 180° and then sat down in the first chair.

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Table 2.

Ambulation parameters vs age and time since diagnosis.

Correlation between age or time since diagnosis and ambulation parameters at free and fast speed (A); parameter changes from free to fast speed (B). R, correlation coefficient; Δ, change from free to fast speed.

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Fig 2.

Age and contributions of step length and cadence change to increased ambulation speed.

Contributions of step length (CSL, ΔSL/ΔSP) and cadence (CCAD, ΔCAD/ΔSP) to speed (SP) increase, as a function of age in all controls (A) and age-matched controls (B).

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Fig 3.

Mean ambulation characteristics in all subjects groups.

Results expressed in mean±SEM, as absolute values of speed, step length and cadence (A), and percent change in parameters from free to fast speed (B). ***, p < 0.001, **, p < 0.01 (pairwise comparisons, ANOVA).

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Fig 4.

Contributions of step length and cadence change to increased ambulation speed vs age or time since diagnosis in patients with PD.

Contributions of step length (CSL) and cadence (CCAD) to speed increase as a function of age (A) and time since diagnosis (B). Step length Index (SLI) as a function of age (C), and time since diagnosis (D).

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Fig 4 Expand