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Table 1.

Summary of mosquito population parameters and respective values.

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Table 1 Expand

Table 2.

Summary of mosquito population parameters depending on precipitation and respective representative values.

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Table 2 Expand

Table 3.

Summary of mosquito population controlling parameters and respective representative values.

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Table 3 Expand

Table 4.

Summary of dengue transmission and human population parameters, and respective representative values.

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Table 4 Expand

Fig 1.

Daily maximum and minimum temperatures (a) and precipitation (b), from October 1st, 1995 to September 30th, 2012 in the City of Campinas, São Paulo State, Brazil.

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Fig 1 Expand

Fig 2.

Monthly recorded cases of dengue in the City of Campinas from October 1st, 1995 to September 30th, 2012 (a), and the controlling of mosquitoes by spraying insecticide and/or removing of the breeding sites since 2010 (b,c).

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Fig 2 Expand

Table 5.

Estimated entomological parameters of female mosquito and aquatic phase.

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Table 5 Expand

Fig 3.

Time varying carrying capacity C (a) and the fraction of hatching eggs q (b) during the period of time (October) 1995–2012 (September).

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Fig 3 Expand

Fig 4.

Transition rates σl (a) and σp (b) during the period of time (October) 1995–2012 (September).

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Fig 4 Expand

Fig 5.

Overall mortality rates of aquatic forms (a) and (b) during the period of time (October) 1995–2012 (September).

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Fig 5 Expand

Fig 6.

Mortality rate of adult mosquitoes μm (a) and the oviposition rate ϕm (b) during the period of time (October) 1995–2012 (September).

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Fig 6 Expand

Table 6.

Model FD: Summary of fitted parameters and epidemiological values for four periods, with rf = r(t2) and Id = i(t1)N(t1).

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Table 6 Expand

Fig 7.

Estimation of Model FD in Period 1 (October/1995—September/2000).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 7 Expand

Fig 8.

Estimation of Model FD in Period 2 (October/2000—September/2004).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 8 Expand

Fig 9.

Estimation of Model FD in Period 3 (October/2004—September/2008).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 9 Expand

Fig 10.

Estimation of Model FD in Period 4 (October/2008—September/2012).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 10 Expand

Table 7.

Model PMAL: Summary of fitted parameters and epidemiological values for four periods, with rf = r(t2) and Id = i(t1)N(t1).

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Table 7 Expand

Fig 11.

Estimation of Model PMAL in Period 1 (October/1995—September/2000).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 11 Expand

Fig 12.

Estimation of Model PMAL in Period 2 (October/2000—September/2004).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 12 Expand

Fig 13.

Estimation of Model PMAL in Period 3 (October/2004—September/2008).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 13 Expand

Fig 14.

Estimation of Model PMAL in Period 4 (October/2008—September/2012).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 14 Expand

Table 8.

Model TMAL: Summary of fitted parameters and epidemiological values for four periods, with rf = r(t2) and Id = i(t1)N(t1).

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Table 8 Expand

Fig 15.

Estimation of Model TMAL in Period 1 (October/1995—September/2000).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 15 Expand

Fig 16.

Estimation of Model TMAL in Period 2 (October/2000—September/2004).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 16 Expand

Fig 17.

Estimation of Model TMAL in Period 3 (October/2004—September/2008).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 17 Expand

Fig 18.

Estimation of Model TMAL in Period 4 (October/2008—September/2012).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 18 Expand

Table 9.

Model SIR: Summary of fitted parameters and epidemiological values for four periods, with rf = r(t2) and Id = i(t1)N(t1).

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Table 9 Expand

Fig 19.

Estimation of Model SIR in Period 1 (October/1995—September/2000).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 19 Expand

Fig 20.

Estimation of Model SIR in Period 2 (October/2000—September/2004).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 20 Expand

Fig 21.

Estimation of Model SIR in Period 3 (October/2004– September/2008).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 21 Expand

Fig 22.

Estimation of Model SIR in Period 4 (October/2008—September/2012).

(a) observed incidence (O) and adjusted i (E), (b) m3/m, (c) (h) and (m), and (d) .

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Fig 22 Expand

Fig 23.

Effects of temperature and precipitation considering the fitted parameters of Model FD in Period 1 (October/1995—September/2000).

(a) Fig 7(a) restricted in the interval October/1995—September/1999 (four years), (b) Period 2 (October/2000—September/2004), (c) Period 3 (October/2004—September/2008), and (d) Period 4 (October/2008—September/2012).

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Fig 23 Expand

Fig 24.

Effects of initial introduction of infectious individuals Id considering the fitted parameters of Model FD in Period 1.

(a) Id = 1, (b) Id = 25, (c) Id = 150, and (d) Id = 1000. (Fig 7(a) was obtained using Id = 75).

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Fig 24 Expand

Fig 25.

Effects of the time of introduction of infectious individuals t1 considering the fitted parameters of Model FD in Period 1.

The time of introduction t1 is year 1995: (a) July 1st, (b) September 1st, (c) December 1st, and (d) December 31st. (Fig 7(a) was obtained using October 1st 1995 as t1).

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Fig 25 Expand