Fig 1.
Lateral view of quantitative color-coded right common carotid DSA and the time density curves of ROIs.
(A) Lateral view of quantitative color-coded right common carotid DSA. ROIRA2 was located at the greatest curvature of ACA. ROISSS and ROIRM2 were chosen by drawing an imaginary line (dashed line) parallel to the osteomeatal line to intersect SSS and the insular branch of the right-middle cerebral artery (RM2) respectively. (B) Time density curves of ROIRA2, ROIRM2, and ROISSS. The dashed line intersecting the X-axis perpendicularly indicate the Tmax of ROISSS. The XA-CCTRA2 (double-headed line) was defined as the time difference between the Tmax of ROIRA2 and that of ROISSS; the XA-CCTRM2 (dashed double headed line) was defined as the time difference between the Tmax of ROIRM2 and that of ROISSS.
Fig 2.
Axial view of the time-maximum intensity projection CTP and the time density curve of ROI.
(A) An axial view of the time-maximum intensity projection CTP at the level where the ACA curved anteriorly and posteriorly. ROIA2 was chosen at the dominant ACA; ROIRM2, ROILM2, and ROISSS were designated at the corresponding vessels. (B) Time density curve of ROIA2, ROIRM2, ROILM2, and ROISSS. The dashed line intersected perpendicularly with the X-axis indicated the TTP of SSS. The CT-CCTA2 (double headed line) was defined as the time difference between the TTP of ROIA2 and that of ROISSS; The CT-CCTRM2 (dashed double headed line) was defined as the time difference between the TTP of ROIRM2 and that of ROISSS. The CT-CCTLM2 (dotted double headed line) was defined as the time difference between the TTP of ROILM2 and that of ROISSS.
Table 1.
Distribution of Patient Characteristics between control and vasospasm groups.
Table 2.
Intraclass-classification of Tmax in selected ROIs in DSA, TTP of selected ROIs in CTP, and calculated CCT.
Fig 3.
Correlation between cerebral circulation time defined by CT perfusion and cerebral circulation time defined by digital subtraction angiography.
Correlation between (A) CT-CCTA2 and XA-CCTRA2; (B) CT-CCTA2 and XA-CCTLA2; (C) CT-CCTRM2 and XA-CCTRM2; and (D) CT-CCTLM2 and XA-CCTLM2. Y axis: CT-CCT, X axis: XA-CCT. CT-CCT: Cerebral circulation time defined by CT perfusion. XA-CCT: Cerebral circulation time defined by digital subtraction angiography. The subscripted abbreviations following CT-CCT and XA-CCT show different arterial ROIs used to calculate circulation time. RA2: second segment of right anterior cerebral artery; RM2: second segment of right-middle cerebral artery; LA2: second segment of left anterior cerebral artery; LM2: second segment of left-middle cerebral artery.
Fig 4.
Correlation between GCS and four individual XA-CCTs.
(A) XA-CCTRA2, (B) XA-CCTRM2, (C) XA-CCTLA2, and (D) XA-CCTLM2. GCS: Glascow Coma Scale, XA-CCT: Cerebral circulation time defined by digital subtraction angiography. The subscripted abbreviations following XA-CCT show different arterial ROIs used to calculate circulation time. RA2: the second segment of the right anterior cerebral artery; RM2: insular branch of the right-middle cerebral artery; LA2: second segment of the left anterior cerebral artery; LM2: insular branch of left-middle cerebral artery.
Fig 5.
Correlation between GCS and thee individual CT-CCTs.
(A) CT-CCTA2, (B) CT-CCTRM2, (C) CT-CCTLM2. GCS: Glascow Coma Scale, CT-CCT: Cerebral circulation time defined by CT perfusion. The subscripted abbreviations following CT-CCT show different arterial ROIs used to calculate circulation time. A2: second segment of the dominant anterior cerebral artery; RM2: insula branch of the right-middle cerebral artery; LM2: insular branch of the left-middle cerebral artery.
Fig 6.
Receiver operating characteristic analysis.
(A) Receiver operating characteristic analysis of all XA-CCTs and CT-CCTs. (B) Receiver operation characteristics analysis of all CT-CCTs, MTT and TTP
Table 3.
Different cerebral circulation times, and perfusion parameters between vasospasm and control groups.
Table 4.
Optimal Cutoff Values of Ten all CCT, MTT, and TTP for Predicting Vasospasm.