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Fig 1.

Image of the Patient Setup.

DUONTM immobilization masks were used to fix the head in the translational (lateral, longitudinal, and vertical) and rotational (pitch, roll, and yaw) dimensions.

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Fig 1 Expand

Table 1.

Characteristics of the Patients in the Study.

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Table 1 Expand

Fig 2.

Image Registration Using kV Tubes 1 and 2 with BrainLAB ExacTrac for Patient #2.

(a) DRR image, (b) ExacTrac image, and (c) image registration.

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Fig 2 Expand

Fig 3.

Inter-fractional Setup Variations (mean ± SD) for the 28 Patients.

Setup errors in the (a) lateral (x-axis, left to right), (b) longitudinal (z-axis, superior to inferior), (c) vertical (y-axis, anterior to posterior), (d) pitch, (e) roll, and (f) yaw dimensions.

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Fig 3 Expand

Fig 4.

Histograms and Normalized Curves for the Translation and Rotational Variations.

Setup errors in the (a) lateral (x-axis, left to right), (b) longitudinal (z-axis, superior to inferior), (c) vertical (y-axis, anterior to posterior), (d) pitch, (e) roll, and (f) yaw dimensions.

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Fig 4 Expand

Table 2.

Systematic (Σ) and Random (σ) Errors in the Translational and Rotational Dimensions.

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Table 2 Expand

Table 3.

Calculated CTV to PTV Margins Proposed by Stroom et al.’s [21] and van Herk et al.’s [22, 24] Formulas Based on the Systematic (Σ) and Random (σ) Errors.

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Table 3 Expand

Fig 5.

Spearman Correlation Analysis between the 3D Vector [mm] and PTV Volume [cm3].

*Spearman correlation coefficient ρ = -0.004; p value = 0.985; R2 = 0.005

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Fig 5 Expand