Fig 1.
Individual details of TRF scores (in seconds) and 6MWT results (in meters).
Fig 2.
Percentage of patients losing ambulation in subgroups subdivided according to TRF performance.
Fig 3.
Average 6MWD change over 12 months according to baseline age (<7 years vs > = 7 years) in those with baseline 6MWD< 350 m and in those with baseline 6MWD> = 350 m.
The significant age by 6MWD interaction (p<0.001) indicates that the baseline value of 6MWD has an impact on the 6MWD change only in children older than 7 years.
Fig 4.
Average 6MWD change over 12 months according to baseline age (<7 years vs > = 7 years) in those with baseline TRF < 7 sec and in those with baseline TRF> = 7 sec.
The borderline significant age by TRF interaction (p = 0.06) indicates that the baseline value of TRF has an impact on the 6MWD change only in children older than 7 years.
Fig 5.
Average 6MWT change over 12 months according to baseline values of 6MWD (<350 vs > = 350) in those with baseline TRF < 7 sec and in those with baseline TRF > = 7sec.
There is no 6MWD by TRF interaction, indicating that that the baseline value of 6MWD has the same impact on the 6MWD change according to different baseline TRF values.