Fig 1.
Risk-adjusted rates in bloodstream infection for children expected to have used standard central venous catheters in 16 PICUs in England; symbols = observed rates; lines = smoothed adjusted rates (log scale).
Table 1.
Parameter estimates using in cost-impact analyses and sensitivity analysis.
Table 2.
Cost-impact (value of resources made available) for a range of BSI rates and best and worst case scenarios for the effectiveness of antibiotic-impregnated CVCs.
Bold indicates cost used in base case analysis.
Fig 2.
Probability distribution for the value of resources made available by averting BSI using antibiotic CVCs in all PICUs in England during 2012; 90% of the distribution represented costs greater than the additional cost of purchasing antibiotic CVCs.
Fig 3.
Cost-impact: Number of BSI averted and value of resources made available using antibiotic in place of standard CVCs for a range of baseline rates, assuming each BSI is associated with a mean cost of £10,975.