Fig 1.
Schematic illustration of the preparation of the CSO-g-CM-β-CD@AD-PTX micelle.
Fig 2.
CSO-g-CM-β-CD synthesis and characterization.
Synthetic route of CSO-g-CM-β-CD (A); FT-IR spectra of CSO-g-CM-β-CD and CSO (B) and 1H-NMR spectra of CSO and CSO-g-CM-β-CD in D2O (C).
Fig 3.
AD-PTX synthesis and characterization.
Synthetic route of AD-PTX (A); LC-MS spectra of AD-PTX (B) and 1H-NMR spectra of AD, PTX and AD-PTX in DMSO-d6 (C).
Fig 4.
2D-NOESY NMR spectrum of CSO-g-CM-β-CD@AD-PTX in D2O.
Table 1.
The influence of pH on CSO-g-CM-β-CD@AD-PTX micelle formation.
Fig 5.
Characterization of CSO-g-CM-β-CD@AD-PTX micellar system.
TEM images (A) and size distribution of CSO-g-CM-β-CD@AD-PTX micelles (B).
Fig 6.
Fluorescence scanning analysis with pyrene (A) and critical micelle concentration of CSO-g-CM-β-CD@AD-PTX solution (B).
Fig 7.
In vitro drug release of CSO-g-CM-β-CD@AD-PTX micelle in the PBS with pH = 7.4 (n = 3).
Fig 8.
In vitro cell viability assay of different formulations on U87 MG cells for 72 h (n = 3).