Fig 1.
Flowchart patient selection for patients admitted to the paediatric intensive care unit (PICU) with severe acute respiratory tract infections (SARIs) with one respiratory virus, in the absence of viral co-infections and typical bacterial co-infections in children admitted to Erasmus MC-Sophia between 2007 and 2012.
Table 1.
Baseline characteristics of children admitted to the paediatric intensive care unit (PICU) with severe acute respiratory tract infections (SARIs) or medium care (MC) with acute respiratory tract infections (ARTIs) associated with a single virus infection in the absence of viral co-infections and typical bacterial co-infections at Erasmus MC-Sophia from 2007–2012.
Fig 2.
Flowchart patient selection for patients admitted to medium care (MC) with acute respiratory tract infections (ARTI) with one respiratory virus, in the absence of viral co-infections and typical bacterial co-infections in children admitted to Erasmus MC-Sophia between 2007 and 2012.
Table 2.
Viral pathogens detected with real time reverse transcriptase PCR in respiratory tract samples of patients admitted to the paediatric intensive care unit (PICU) with or without a severe acute respiratory tact infection (SARI) and medium care (MC) admitted patients with or without an acute respiratory tract infection (ARTI) at the Erasmus MC-Sophia over a 5-year period (2007–2012).
Fig 3.
Cycle threshold (Ct) values of all single virus positive samples tested in nasal washings of patients admitted to the paediatric intensive care unit (PICU) with severe acute respiratory tract infections (SARIs) (PICU-SARI patients), all PICU admitted patients, patients admitted to medium care (MC) with acute respiratory tract infections (ARTIs) and all MC admitted patients between 2007 and 2012.
(Note: Ct-values were not available for all samples, *with statistical significant difference).
Fig 4.
A and B. Cycle threshold (Ct) values of positive samples for respiratory syncytial virus (RSV) (A) and human rhinovirus (HRV) (B) tested in nasal washings and compared between patients admitted to the paediatric intensive care unit (PICU) with severe acute respiratory tract infection (SARI) (PICU-SARI patients), all PICU admitted patients, patients admitted to medium care (MC) with acute respiratory tract infections (ARTIs) (MC-ARTI patients) and all MC admitted patients.
(Note: Ct-values were not available for all samples).