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Fig 1.

Example of different ZHF patch locations on the head of a euthanized pig.

The patch is located at position B (obliquely above the eye), circles indicate placement at location A (directly behind the temporal corner of the eye) and C (centered on the forehead).

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Fig 1 Expand

Fig 2.

Pattern of mean temperatures during cooling (black) and maintaining phase (grey) at ZHF locations A (4 pigs), B (3 pigs) and C (4 pigs). Data points represent the mean temperature (TZHF or Tpulm) of the respective group for each time point (every 5 minutes). Number of paired measurements at ZHF location A: n = 130, at ZHF location B: n = 98, at ZHF location C: n = 135. Tpulm = blood temperature in the pulmonary artery; TZHF = temperature measured by the ZHF device.

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Fig 2 Expand

Fig 3.

Bland Altman plots comparing Tpulm and TZHF for ZHF location A (4 pigs), B (3 pigs) and C (4 pigs) during cooling and maintaining phase. Tpulm = blood temperature in the pulmonary artery, TZHF = temperature measured by the ZHF device.

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Fig 3 Expand

Table 1.

Bias of TZHF and Tpulm for each ZHF location (A, B, C) in cooling phase, maintaining phase and the time effect.

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Table 1 Expand

Table 2.

Time delay of TZHF compared to Tpulm during the cooling phase.

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Table 2 Expand