Fig 1.
Structural information of the 11 antimicrobial SecA inhibitors identified using similarity search method.
Table 1.
Names, formulas, and chemical properties of sixteen compounds tested in this study.
Table 2.
Results of surfactant screening assay.
Table 3.
Optimization results of three component surfactant system containing different weight ratios of Emulpon CO-360, Tergitol L-61, and Rhodafac RE-610.
Table 4.
Effects of various concentrations of MMX on germination, root length, stem length, as well as root and stem fresh weight of Citrus × sinensisz.
Table 5.
MICs and MBCs of sixteen antimicrobial SecA inhibitors against bacteria (μg/mL).
Fig 2.
SecA of Las ATP Binding site is displayed as molecular surface interface and labeled the critical residues Phe58, Arg112, Arg344 on the surface of the model.
NP1, NP2 are the newly identified pockets at the ATP binding site of SecA. The docked ligands were represented in stick model and they are a).ATP, b).SA1, c).SA2, d).SA3, e).SA4, f).SA5, g).SA6, h).SA7, i).SA8, j).SA9, k).SA10 & l).SA11. PyMOL program was used to build the protein surface models.