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Table 1.

Summary data on radiation-associated cancer risk and various tissue parameters, reproduced in part from Tomasetti & Vogelstein [2] and UNSCEAR [unless otherwise indicated taken from Table 70 in Annex A of [14]]

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Table 2.

Summary data on smoking-associated cancer risk and various tissue parameters, reproduced in part from Tomasetti & Vogelstein [2] and Doll et al. [15]

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Table 2 Expand

Table 3.

Linear regression fits of model (9) to data of Tomasetti and Vogelstein [2]a, and in some cases omitting tumors with short latency (leukemia, bone, thyroid).

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Table 4.

Trends of linear regression model (11) fitted to radiation exposure-induced cancer incidence risk (REIC)(percent) (or log10[REIC]) with explanatory variables (a) numbers of stem-cell divisions per year (or log10[numbers of stem-cell divisions per year]), (b) log10[cumulative number of stem-cell divisions], (c) extra risk score (ERS) and (d) log10[number of stem-cells], using data of Tomasetti and Vogelstein [2], as in Table 1.

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Table 5.

Trends of linear regression model (12) fitted to mortality rate difference [current smokers–former smokers] (/105 /year) with explanatory variables (a) numbers of stem-cell divisions per year, (b) log10[cumulative number of stem-cell divisions], (c) extra risk score (ERS) and (d) log10[number of stem-cells], using data of Tomasetti and Vogelstein [2], as in Table 2.

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Table 6.

Trends of linear regression model (13) of log10[US lifetime natural cancer incidence risk] vs log10[cumulative stem-cell divisions]among cancer sites with available radiation risk (Table 1) or smoking risk (Table 2) data, and in the dataset of Tomasetti and Vogelstein [2], and in some cases omitting tumors with short latency (leukemia, bone, thyroid).

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