Fig 1.
Deprescribing Algorithm.
Fig 2.
Recruitment and Participation.
Table 1.
Baseline demographic and clinical data.
Fig 3.
“Withdrawal Achieved” means medicine ceased or changed to PRN used less frequently than once per week at the last follow-up assessment point; RN, registered nurse; NOK, next of kin; GP, general practitioner. Percentages for “Withdrawal Failed” and “Withdrawal Achieved” are calculated as a percentage of the “Withdrawal Attempted” total. Italic numbers in () in the two large explanatory boxes refer to number of people.
Table 2.
Withdrawal success rates for medicines deprescribed in ten or more participants.
Fig 4.
Change in the mean number of regular medicines per person.
Closed bars are the intervention group. Open bars are the control group. Error bars are 1 SEM.
Table 3.
Cognitive function, independence in ADLS, sleep quality, self-assessed quality of life, self-assessed general health.
Table 4.
Change in bowel function following deprescribing.
Table 5.
Adverse outcomes.
Fig 5.
Kaplan Meier survival plot to 12 months post-randomisation.