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Fig 1.

Standard curve validation of A) SPARC (R2 = 0.999) and B) PR3 (R2 = 0.996).

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Fig 2.

Reproducibility study results of A) SPARC and B) PR3.

Three urine samples with low, medium and high concentration were used.

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Fig 3.

Linearity results of A) SPARC and B) PR3.

For each biomarker a high concentration sample was serially diluted and theoretical values were compared to the experimental.

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Fig 3 Expand

Table 1.

Summary of analytical performance.

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Table 1 Expand

Table 2.

Recovery study results of SPARC. Negative urine samples were spiked with low, medium and high concentration of standard.

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Table 2 Expand

Table 3.

Recovery study results of PR3. Negative urine samples were spiked with low, medium and high concentration of standard.

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Table 3 Expand