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Fig 1.

Flow-chart of the study.

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Table 1.

Demographic and clinical characteristics of training and validation cohorts.

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Table 2.

Assignment of weights in the construction of DDCI through a time-to-death multivariate Cox proportional hazards regression.

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Fig 2.

Kaplan-Meier curves according to DDCI score value.

Panel A: overall survival; Panel B: time to first hospitalization.

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Table 3.

Hazard Ratios for overall mortality adjusted by age and sex, according to DDCI.

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Table 4.

Incidence rates (IR) per person-years of total hospital readmissions in the validation set and incidence rate ratios (IRR) according to DDCI score (the lowest class is the reference category).

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Table 5.

Discrimination and reclassification analysis.

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