Fig 1.
Before CT-MPI analysis, nonevaluable with CCTA was defined as positive for stenosis using the following criteria: those with no vessel wall definition owing to marked motion artifacts or heavy calcification that precluded acquisition of diagnostic information.
Table 1.
Patients’ characteristics.
Fig 2.
Case examples of CCTA, CT-MPI without stress, coronary angiography, and invasive FFR.
Case 1. CCTA showed significant coronary artery calcification in the proximal LAD (yellow arrow). CT-MPI without stress showed no perfusion defect. Coronary angiography confirmed no significant stenosis in the LAD with invasive FFR = 0.86. Case 2. CCTA showed significant coronary artery calcification in the left main trunk and proximal LAD (yellow arrow). CT-MPI without stress showed perfusion defects in the anterior (yellow arrow) and inferior (green arrow) walls. Coronary angiography confirmed 58% luminal stenosis in the LAD with invasive FFR = 0.78 (yellow line) and 56% stenosis in the RCA (green arrow). Case 3. CCTA showed diffuse stenosis <50% in the middle of the LAD (yellow arrow). CT-MPI without stress showed perfusion defects in the anterior (yellow arrow) and inferolateral (green arrow) walls. Coronary angiography confirmed diffuse 55% stenosis in the LAD with invasive FFR = 0.75 (yellow line) and 69% of luminal stenosis in the LCx. LCx, left circumflex artery; RCA, right coronary artery.
Fig 3.
Agreement for detection of ischemia (FFR ≤0.80) between CCTA and CCTA + CT-MPI without stress on a per-vessel basis.
Data given as number (%); n = 75 vessels.
Table 2.
Diagnostic accuracy of CCTA and CCTA plus CT-MPI without stress for detection of significantly stenotic coronary arteries in 75 vessels.