Fig 1.
Flow diagram of cases of invasive pneumococcal disease, South Africa, 2003–2008 (n = 27 632).
Fig 2.
Incidence of invasive pneumococcal disease by age category and year, South Africa, 2003–2008 (n = 17 604).
Footnote: Between 2003 and 2004 there was a significant increase in disease (p<0.001), most notably in the 20–49 year age group (p<0.001), however from 2005 to 2008 disease incidence did not change significantly overall, however a small decrease was noted in the 5–19 year age group (p = 0.004).
Fig 3.
Incidence of invasive pneumococcal disease (IPD) amongst HIV-uninfected and HIV-infected persons by age category, South Africa, 2008.
Table 1.
Annual incidence and relative risk of invasive pneumococcal disease amongst HIV- infected and -uninfected persons by age category, South Africa, 2008.
Fig 4.
Incidence of invasive pneumococcal disease among persons 5 years and older by the commonest 15 serotypes causing disease, South Africa, 2003–2008 (n = 17 604).
Footnote: * Significant changes during the established surveillance period (2005–2008) were seen in serotype 1 (p<0.001) (down), 4 (0.02) (up), 6A (p = 0.0486) (down), 19F (p = 0.0306) (down), 12F (p = 0.0037) (down), 18C (p = 0.0368) (up). Of 17 604 cases of IPD, serotype data were missing and thus imputed for 5 041 cases.
Table 2.
Comparison of individuals with invasive pneumococcal disease identified at enhanced versus non-enhanced surveillance sites, South Africa, 2003–2008 (n = 17 604).
Table 3.
Comparison of HIV-infected and HIV-uninfected patients (5-years and older) with invasive pneumococcal disease, South Africa, 2003–2008 (n = 4 734).