Table 1.
Baseline demographic and clinical characteristics.
Table 2.
Characteristics of hormonal contraceptive use.
Table 3.
Association between combined oral contraceptives and MS (n = 239 cases/2322 controls).
Fig 1.
Association between combined oral contraceptive use and multiple sclerosis/clinically isolated syndrome.
Ever using COCs, regardless whether current or former, was associated with a slight increased risk of MS/CIS (p<0.001; p = 0.02; and p = 0.001 respectively). Longer duration of use (1stshortest -5thlongest quintiles) did not result in any change in risk. OR are adjusted for parity, miscarriage/abortions, smoking and obesity.
Table 4.
Association between combined oral contraceptives and MS/CIS.
Table 5.
Association between Progestin Content of COC and MS/CIS.