Table 1.
Characteristics of healthy control subjects.
Fig 1.
Scatter-plot of the neighborhood SES and alpha-diversity.
Figs depict associations between neighborhood SES and alpha-diversity in biopsies excised from sigmoid mucosa (upper plots) and feces collected from sigmoid lumen (lower plots). Shannon and Chao1 indices are different metrics for calculating alpha-diversity.
Fig 2.
Map depicting the neighborhood SES and alpha-diversity.
Map of greater Chicago region, illustrating associations between neighborhood SES and alpha-diversity in biopsies excised from sigmoid mucosa. Depicted are neighborhood SES (left panel), and two metrics of diversity, the Shannon (middle panel) and Chao1 (right panel) indices. For each variable, the sample was divided into quartiles, and neighborhoods were colored as follows: Red = lower 25% of sample; Yellow = 26–50%; Green = 51–75%; Blue = upper 25%. Geospatial data sources: Urban place area from TIGER/Line US Census 2010; Illinois and Wisconsin zip codes from TIGER/Line US Census 2010; Water area from TIGER/Line US Census 2010; Interstate lines from TIGER/Line US Census 2010.
Table 2.
Results of linear regression analyses predicting alpha-diversity indices from neighborhood SES.
Table 3.
Results of adjusted linear regression analyses, predicting alpha-diversity indices from neighborhood SES, plus demographic and lifestyle covariates.
Fig 3.
Scatter-plot of neighborhood SES and bacterial genera.
Figs depict associations between neighborhood SES and Prevotella to Bacteroides ratio (upper panel), as well as relative abundance of Prevotella (middle panel) and Bacteroides (lower panel). Specimens are biopsies excised from sigmoid mucosa.
Table 4.
Spearman rank-order correlations between neighborhood SES and bacterial genera reflecting sigmoid mucosal enterotypes.