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Fig 1.

Flowchart of the study population.

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Table 1.

Characteristics of the VVR and control groups (1).

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Table 1 Expand

Table 2.

Characteristics of the VVR and control groups (2).

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Table 2 Expand

Fig 2.

Trend test for the male subgroup (VVR-control ratio).

The trend test was significant (p<0.001), and the quartiles were: Total protein (Q1,<6.9; Q2,<7.2; Q3,<7.5; Q4,≥7.5), Albumin (<4.5; <4.7; <4.9; ≥4.9), Hemoglobin (<14.5; <15.1; <15.7; ≥15.7).

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Fig 2 Expand

Fig 3.

Trend test for the female subgroup (VVR-control ratio).

The trend test was significant (p<0.001), and the quartiles were: Total protein (Q1,<6.9; Q2,<7.2; Q3,<7.5; Q4, ≥7.5), Albumin (<4.4; <4.6; <4.8; ≥4.8), Hemoglobin (<12.7; <13.2; <13.7; ≥13.7).

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Fig 3 Expand

Table 3.

Multivariate analysis of VVR risk.

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Table 3 Expand

Table 4.

Multivariate analysis of VVR risk in sex subgroups.

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Table 4 Expand