Fig 1.
(A) Sagittal View of MLF ROI (red) overlaid on MNI atlas.(B) Axial View of left (blue) and right (red) MLF ROI.
Fig 2.
DTI measures with spline fits.
Diffusion tensor-derived values at different slice locations (mm in Inferior-Superior direction in MNI space) along with penalized spline fits (solid lines: fit, dashed lines: 95% confidence intervals). Controls are on the left in blue (A,C,E,G), patients on the right in red (B,D,F,H). Parameters are LD (A,B), TD (C,D), MD (E,F) and FA (G,H).
Fig 3.
Comparison between patients and controls.
Comparisons between controls (blue) and patients (red) of penalized spline fits (solid) and 95% confidence intervals (dashed) of A) LD, B) TD, C) MD and D) FA. Medulla-pons corresponds to coordinates between vertical black dashed lines in A.
Fig 4.
Correlation between VDI measures and LD in the medulla-pons region along with a regression line.