Fig 1.
Flow chart of the study population.
Abbreviations: DM, diabetes mellitus; eGFR, estimated glomerular filtration rate.
Table 1.
Baseline characteristics and average values during follow-up according to eGFR and proteinuria levels at the time of renal biopsy.
Table 2.
Number of patients and incidence rates of renal outcome stratified by eGFR and proteinuria levels.
Fig 2.
Event-free survival of renal events stratified by eGFR and proteinuria categories.
A: eGFR ≥60 mL/min/1.73 m2. B: eGFR 30 to <60 mL/min/1.73 m2. C: eGFR <30 mL/min/1.73 m2. Abbreviation: eGFR, estimated glomerular filtration rate.
Table 3.
Association of clinical parameters with the risk for renal events.
Fig 3.
Joint association of baseline eGFR and proteinuria levels on the risk for renal events.
Estimates are adjusted for baseline covariates, including age, sex, BMI, systolic blood pressure, smoking history, past history of CVD, serum albumin, serum uric acid, C-reactive protein, hemoglobin, and ACEIs/ARBs. The subgroup in the highest eGFR (≥60 mL/min/1.73 m2) and normal/mild proteinuria (<0.5 g/day) is the referent. Abbreviations: eGFR, estimated glomerular filtration rate; BMI, body mass index; CVD, cardiovascular disease; ACEIs, angiotensin-converting enzyme inhibitors; ARBs, angiotensin receptor blockers.