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Fig 1.

Monthly number of HFMD cases reported in mainland China, 2008–2012.

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Fig 2.

Yearly kernel density map of HFMD incidence in mainland China 2008–2012 (A-E).

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Fig 2 Expand

Fig 3.

Locations (A) and time characteristics (B) of the four different categories based on the time distribution of every county with at least one monthly case.

The line graph is the average of the counties under the same classification.

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Fig 3 Expand

Table 1.

Results of the spatial autocorrelation test on HFMD incidences at the county level in mainland China, 2008–2012.

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Table 1 Expand

Fig 4.

Spatial correlation cluster maps for HFMD incidence, 2008–2012 (A-E).

HH, high-high cluster; HL, high-low cluster; LH, low-high cluster; LL, low-low cluster.

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Fig 4 Expand

Fig 5.

Local Indicators of Spatial Association (LISA) significance maps for the incidence of HFMD in mainland China, 2008 (A) to 2012 (E).

Red indicates concentrated outbreaks, and blue indicates a low incidence.

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Fig 6.

Spatiotemporal clusters of HFMD in mainland China, 2008–2012(A-E).

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Table 2.

The most likely space-time clusters of HFMD in mainland China, 2008–2012.

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Table 2 Expand

Table 3.

Distance from the provincial capital city of clustered counties and non-clustered counties, 2008–2012.

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Table 3 Expand

Fig 7.

Detected times of spatiotemporal clusters of HFMD in mainland China, 2008–2012.

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Fig 7 Expand