Table 1.
Demographic characteristics of UC patients and the controls.
Table 2.
Amplification and extension primers of FUT2 and FUT3.
Table 3.
Allelic and genotypic distributions of FUT2 and FUT3 between UC patients and the controls.
Fig 1.
Linkage disequilibrium patterns of FUT2 and FUT3 in Chinese Han populations.
Numbers indicated the percentage of D' between 2 SNPs and in the dark area which have no digital represents D' = 1. Dark color indicated strong connection. Block 1 illustrated linkage disequilibrium in the 3 SNP in FUT3, and block 2 showed that rs281377 was in linkage disequilibrium with rs1047781 in FUT2.
Table 4.
Haplotype frequencies of FUT2 and FUT3 in patients with UC and the controls.
Table 5.
Association of FUT2 and FUT3 polymorphisms with clinical characteristics of UC patients.
Fig 2.
Representative Sigmoid Colon specimens of UC patients and patients with benign colonic polyps.
Expression of Lewis a antigen (a-c) and Lewis b antigen (d-f) in the sigmiod specimens of inflammatory and adjacent non-inflammatory tissue of UC patients and normal controls. Samples a, b, d, e were derived from patient 5, described in Table 6. Samples c and f were derived from normal tissue of patients with benign colonic polyps. Immunohistochemical staining indicated increased expression of Lewis a antigen in the cryptic epithelium in inflammatory lesions from UC patients and normal mucosa from patients with benign colonic polyps (see arrows in a-c). Expression in the epithelium did not differ dramatically between UC patients and patients with benign colonic polyps. Expression of Lewis b antigen did not differ dramatically between the three groups (d–f).
Table 6.
Demographic characteristics of UC patients for immunohistochemistry study.