Table 1.
Selection criteria according to the STIKO.
Table 2.
Risk of bias assessment of the identified clinical trials.
Fig 1.
Integrative flowchart of relevant full-texts identified by literature search used in Moberley et al. 2013 and by literature search update from 2012–2014.
Table 3.
Study characteristics of the identified clinical trials.
Table 4.
Baseline characteristics of subjects# included in the identified clinical trials.
Table 5.
Primary analysis of the number# of patients experiencing a pCAP.
Fig 2.
Forest Plot of PPV23 efficacy to prevent pCAP stratified by study setting.
Table 6.
Key results of the meta-analysis.
Table 7.
Primary analysis of the number# of patients experiencing an all-cause CAP.
Fig 3.
Forest Plot of PPV23 efficacy to prevent all-cause CAP by study setting.
Fig 4.
Forest Plot of PPV23 efficacy to prevent all-cause CAP by continent of trial (without study setting “Nursing home”).