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Fig 1.

Flow diagram describing participant contactability, recruitment and exclusion from Phase 1 to Phase 3.

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Table 1.

Proportion of myopes and incidence of myopia between Phase 1 and 3.

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Table 1 Expand

Table 2.

Proportion of hyperopes and decline of hyperopia between Phase 1 and 3.

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Fig 2.

Scatterplots of SER at Phase 1 versus SER at Phase 3 for the younger and older cohorts respectively.

Data are grouped into refractive classifications as illustrated in the key. The gray boxes indicate participants who became myopic (younger cohort n = 27; older cohort n = 8) or lost their hyperopia (younger cohort n = 20; older cohort n = 4) between Phase 1 and 3. The dashed lines represent the myopia cut-off point of -0.50D or less and the dotted line represents the hyperopia cut-off of +2.00D or greater. The solid black line represents unity- those falling below the line are showing a myopic change in SER.

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Fig 3.

Comparison of refractive error prevalence in the UK (NICER Study) to Australia (SMS/SAVES) at baseline and 5–6 year follow-up.

The brackets show the statistical comparisons of the proportions of myopes between the two studies; black indicates statistically significant difference, gray indicates no statistically significant difference (Two sample test of proportion).

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Fig 4.

Comparison of UK refractive error distribution between 1950’s-1960’s (Sorsby study) and 2006–2014 (NICER study) at baseline and follow-up.

The brackets indicate the statistical comparisons of the proportions of myopes between the two studies; black indicates statistically significant difference, gray indicates no statistically significant difference (Two sample test of proportion).

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Fig 4 Expand

Fig 5.

Distribution of spherical equivalent refractive errors in 6–7 year old children within the NICER study Phase 1 (2006–2008) and 6–7 year old children from Sorsby et al.[14].

Data points represent a one dioptre interval (for example, the % of participants represented at point 0 on the x-axis have an SER of less than or equal to 0DS but greater than -1 DS. Data points at the extremes of the x-axis represent participants with SER of greater than or equal to +5DS or less than or equal to -5DS.

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Fig 5 Expand

Table 3.

Comparison of the incidence and progression of myopia between the NICER and Sydney studies for the younger and older cohorts.

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Table 3 Expand