Fig 1.
Weight-bearing system of the proximal femur and trabecular column extracted from QCT and mechanical test.
The primary (PCT) and second compressive trabeculae (SCT) were delineated in the figure. After extracted from femoral head, PCT was cut into three segments. The first segment was ~25% of the diameter of the femoral head and the second segments was ~20%. The green box shows the extracting channel of the femoral head, while the blue box shows the 20% diameter length of the trabecular column that was used for the QCT scan and mechanical test. The red arrow indicated the loading direction of mechanical test. a, The femoral neck area of interest (NN); b, the trochanteric area of interest (IT); and c, the shaft area of interest (FS) during the analysis of BMD and HSA.
Table 1.
Background data of study subjects (n = 53; mean ± SD).
Table 2.
Pearson’s correlation of the acoustic parameters with the BMD of the proximal femur DXA
Fig 2.
Pearson’s correlations between BMD values from the QUS, QCT, and DXA studies.
The Est.BMD significantly correlated with the Tra.BMD (Fig 2a). The QUI significantly correlated with the Tra.BMD (Fig 2b). The BMD-QCT significantly correlated with the Tra.BMD (Fig 2c). The Tra.BMD indicates the BMD of the trochanteric area.
Table 3.
Pearson’s correlation of the acoustic parameters and the mechanical test of the PCT with HSA analysis of the proximal femur.
Fig 3.
Pearson’s correlation of QUS-derived stiffness and HSA-derived parameters of the trochanteric area.
The QUI was significantly correlated with IT.CSA (Fig 3a), IT.CSMI (Fig 3b), IT.Z (Fig 3c) and IT.BR (Fig 3d). The IT.CSA, IT.CSMI, IT.Z and IT.BR indicate the CSA, CSMI, Z and BR of the trochanteric area.
Table 4.
Pearson’s correlation of the acoustic parameters with the HSA of the proximal femur cortical measurement
Fig 4.
Pearson’s correlation of stiffness with mechanical properties of the primary compressive trabecular (PCT) column in the femoral head.
The QUI significantly correlated with Young’s modulus of the PCT column of the femoral head (Fig 4a). However, no significant correlation was noted with the yield strength (Fig 4b), or ultimate strength (Fig 4c).