Fig 1.
An 80-MHz Ultrasound Biomicroscopy Image of Schlemm’s Canal and the Trabecular Meshwork in a Normal Individual.
Schlemm’s canal (red arrow) and the trabecular (white arrow) are apparent in the image.
Fig 2.
Example of Schlemm’s Canal and Trabecular Meshwork Measurements Made Using the iUltrasound Imaging System.
The black oval space shows Schelmm’s canal (SC). The meridional diameter of SC was measured from the anterior (a) to the posterior (b) end point of SC. To measure the coronal diameter of SC, we drew a vertical line across the canal to get two intersection points (c and d). The maximum distance between c and d was taken as the coronal diameter of SC. Lines 1, 2 indicated where trabecular meshwork thickness was measured and the dotted line shows the meshwork inner layer.
Table 1.
Subject and Ocular Characteristics.
Table 2.
Proportion of Eyes with an Observable Schlemm’s Canal.
Table 3.
Proportion of Eyes with Primary Open Angle Glaucoma That Had an Observable Schlemm’s Canal.
Table 4.
Characteristics of Schlemm’s Canal.
Table 5.
Trabecular Meshwork Thickness.
Fig 3.
Schlemm’s Canal Meridional and Coronal Diameter and Trabecular Meshwork Thickness in Patients with Primary Open Angle Glaucoma.
Schlemm’s canal (SC) and trabecular meshwork (TM) measurements for patients with primary open angle glaucoma (POAG) and normal IOP (< 21 mmHg) and patients with POAG and elevated IOP (> 21 mmHg). *indicates a statistically significant difference.
Fig 4.
Correlations between Schlemm’s Canal Coronal Diameter, Trabecular Meshwork Thickness, and Intraocular Pressure.
Schlemm’s canal coronal diameter and trabecular meshwork thickness were both significantly and negatively correlated with intraocular pressure in patients with primary open angle glaucoma.