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Table 1.

Definitions of (a) reporting and (b) design characteristics.

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Fig 1.

Quality of reporting.

Proportion of validation studies with adequate and inadequate description of reporting characteristics.

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Fig 2.

Evolution of methodological quality over time.

Proportion of validation studies satisfying (a) reporting characteristics and (b) design characteristics recommended in methodological standards.

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Fig 3.

Influence of design characteristics on the performance of clinical prediction rule in multivariable analysis.

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Fig 4.

Fagan nomogram.

Applying the sensitivity and specificity of (a) 90% as presented in the validation study [58] and (b) 81% from an unbiased study to a patient with 10% probability of rheumatoid arthritis.

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Fig 4 Expand