Fig 1.
Prior to study enrolment, patients were examined for sleep disorders through 1 night of polysomnography (PSG) evaluation, sleep diary and actigraphic data. Prior to therapy, a baseline assessment of sleep with half hourly blood and minutely core body temperature measures was implemented. Sleep restriction therapy was initiated over the course of 5 weeks with daily sleep diaries, actigraphic recordings and weekly questionnaire assessments including: the Insomnia Severity Index: ISI; Sleep Restriction Adherence Scale: SRAS. After 6 weeks, patients returned for a post-treatment overnight study again with overnight measures of both blood and temperature.
Fig 2.
Study CONSORT flow diagram.
Table 1.
Sleep diary variables.
Fig 3.
Cortisol concentrations across the night pre-to-post sleep restriction therapy.
Mean nocturnal cortisol secretion (n = 6) for each sample collection time point (baseline and post treatment) is displayed over the course the night (22:00–06:00). Error bars indicate one standard error of the mean. Cortisol (μg/dL-1). (*) = p < .05.
Fig 4.
Core body temperature across the night pre-to-post sleep restriction therapy.
Mean nocturnal core body temperature in degrees Celsius (°C) (n = 6) for each sample collection time points (baseline and post treatment) is displayed over the course the night (22:00–06:00). Error bars indicate one standard error of the mean. (*) = p < .05.