Fig 1.
Lyso-Gb3 analogues and Gb3 Isoforms.
(A) Chemical structure of Lyso-Gb3 and sphingosine modification of lyso-Gb3 analogues. (B) Chemical structure of Gb3(d18:1-C16:0) and ceramide modification of Gb3 isoforms having various fatty acids linked with various sphingosine moieties corresponding to lyso-Gb3 and four analogues.
Table 1.
The target masses and acquisition times of Gb3 Isoforms.
Table 2.
Gb3 and lyso-Gb3 concentrations in the wild-type and GLA knockout mice.
Fig 2.
The distributions of Gb3 isoforms in organs and plasma of the wild-type and GLA knockout mice.
Numbers along the x-axis are elution orders from the RP column and correspond to numbers in Table 1.
Fig 3.
The relative abundance of lyso-Gb3 analogues as to lyso-Gb3 in organs and plasma of the wild-type and GLA knockout mice.