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Fig 1.

Distribution of the length of transcript assembly unigenes.

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Table 1.

Summary of short-read data from hydrangea produced by Illumina sequencing.

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Table 2.

The length distribution of assembled contigs, transcripts and unigenes.

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Table 3.

Annotation of Unigenes were searched against from NR, SwissProt, GO, KOG, KEGG by BLAST.

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Fig 2.

The overview of differential expression between no Al and Al stress in roots and leaves in hydrangea.

(A) Boxplots of the DEGs in the four samples; (B) Sequencing saturation level analysis of DEGs in the four samples; (C) Density distribution of the differentially expressed genes (DEGs) in the four samples; (D) heat map of the DEGs in roots and leaves between Al(-) and Al (+).

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Fig 3.

Histogram of KOG classification of differential expressed unigenes in roots (A) and leaves (B) under Al stress in hydrangea.

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Fig 4.

Gene Ontology classifications of differential expressed unigenes in roots (A) and leaves (B) under Al stress in hydrangea.

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Fig 5.

KEGG enrichment analysis of differential expressed unigenes in roots (A) and leaves (B) under Al stress in hydrangea.

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Fig 6.

Validation of the expression data from RNA-seq analysis via quantitative real-time RT-PCR (qPCR) analysis.

Twenty genes exhibiting diverse expression profiles in the RNA-seq data were chosen for qPCR analysis. Average value of each RNA-seq expression data was plotted against that from qPCR and fit into a linear regression. Both x- and y-axes were shown in log2 scale.

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Table 4.

Comparison of expression profiling between STOP/ART-regulated genes in rice or Arabidopsis and corresponding genes in hydrangea roots.

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Fig 7.

Expression analysis of differential expression unigenes in root and leaves under Al stress in hydrangea by quantitative real-time RT-PCR (qPCR).

Eighteen genes in roots: ABC (c166032.graph_c0), ABC transporter B family member 12; AtpJ (c176296.graph_c0), ATP synthase subunit J; CHA (c149908.graph_c2), Chitinase-like protein; COX11 (c220486.graph_c0), Cytochrome c oxidase assembly protein COX11; CWP(c193058.graph_c1), Cell wall protein DAN4; DDI (c201184.graph_c0), DNA damage-inducible protein 1; GAT (c211725.graph_c0), Glucose/galactose transporter; HMT (c205800.graph_ c0),Heavy metal tolerance protein; MAD (c86593.graph_c0), Malate dehydrogenase; MAP(c119898.graph_c0), malate carrier protein; MFS(c219821. graph_c0), Major facilitator superfamily; MHF(c185758. graph_c0), Metal homeostasis factor ATX1; MMA1 (c152377.graph_c0), Mitochondrial metalloendopeptidase; MMT1(c142806.Graph_c0), Mitochondrial metal transporter 1; PCD6 (c127753.Graph _c0), Programmedcell death protein 6; MRA (c211816.graph_c0), Multidrug resistance- associated protein 1; MYB (c156038. graph_c0), Myb-like protein; SUP(c161922.graph_c0), Subtilisin-like proteinase Spm1. Two genes in leaves: AMT (c208330. graph_ c1), Aluminum-activated malate transporter; POT (c86493.graph_c0), Potassium transporter 1. The asterisks indicate significant differences between root (+Al) and root (-Al), or leaves (+Al) and leaves (-Al), as determined by Student’s t test (*P<0.05, **P < 0.01, ***P < 0.001).

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Table 5.

Al-induced transporter genes in hydrangea roots.

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Table 6.

Al-induced transporter genes in Hydrangea leaves.

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Table 7.

Classification of SSR repeats in the hydrangea transcriptome assembly.

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Fig 8.

SNP distribution of different variation types in hydrangea.

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